GCMS-ISQ – Thermo

Location : 2^nd floor  East, room 2S24

The CESAMO platform is equipped with two GC/MS ISQ (ThermoFisher) mass spectrometer coupled to a gas chromatography apparatus. They are equipped with a quadrupole analyzer. There are several possibilities for introducing the sample : either by standard gas chromatography, or in “headspace” mode which enables volatile compounds to be analyzed, or in pyrolysis mode which enables the study of macromolecular compounds.  The range of analyzable masses extends from 1 to 1000 m/z. The different sources of ionization are EI (Electronic Ionization), PCI (Positive Chemical Ionization) and NCI (Negative Chemical Ionization).

 This instrument is used :

• For the qualitative and quantitative analysis of mixtures or pure non-thermolabile products with masses less than 1000.
• For the characterization of polymers by pyrolysis.

L’article GCMS-ISQ – Thermo est apparu en premier sur Cesamo.

Accutof – JEOL

Location : 2^nd floor  East, room 2N24

The AccuToF Mass Spectrometer (Jeol) is a GC-TOF type mass spectrometer acquired in 2011. Its resolving power is greater than 6000 at 617 Da mass. The range of analyzable masses is between 0 and 4000 m/z. The measurement accuracy is less than 5 ppm in external calibration. The different possible sources are: EI (Electronic Ionization), CI (Chemical Ionization) and FI / FD (Ionization / Field Desorption). It can work in coupling with a gas chromatograph or in direct introduction mode.

This instrument is used :

• For high-resolution mass measurements (determination of molecular formulas) on pure or mixed products (high-resolution GC / MS coupling).
• For the analysis of non-polar compounds in high resolution

L’article Accutof – JEOL est apparu en premier sur Cesamo.

Autoflex Bruker

Location : 2^nd floor  East, room 2N24

The Autoflex Mass Spectrometer is a MALDI-type mass spectrometer equipped with a ToF analyzer, acquired in 2019. Its resolving power is 26,000. The range of masses that can be studied extends from 200 to 350,000 m/z. The laser used is of the Smartbeam type. This device is also equipped with a FAST system particularly suitable for the study of peptides, for example :

• This instrument can be used for the analysis of molecules of high masses: polymers and proteins.
• In the case of the study of polymers, it allows the determination of chain ends (for masses less than 20,000), confirmation of the monomer unit, calculation of the molar mass and of the polymolecularity

L’article Autoflex Bruker est apparu en premier sur Cesamo.

Qexactive – Thermo

Location : 2^nd floor  East, room 2N24

It is an orbitrap-type mass spectrometer that was acquired in 2018. It has a resolving power of 140,000 FWHM (Full Width at Half Maximum). The range of masses that can be analyzed with this type of device extends from 50 to 6000 m/z. The precision of the mass measurement is less than 1 ppm in internal calibration and less than 3 ppm in external calibration. This instrument is equipped with an ESI (Electrospray) ionization source. This instrument is used in conjunction with Vanquish liquid chromatography.

This instrument is used :

• for mass measurements in high resolution (determination of molecular formulas) on pure or mixed products (LC / MS coupling in high resolution).
• For specific studies relating to the MS/MS mode.

L’article Qexactive – Thermo est apparu en premier sur Cesamo.